Overview of coupling reagents for amide and ester formation in the chemical reaction database

Coupling reagents

compound name
2,2′-dipyridyl disulfide DPS Go
2,4,6-trichlorobenzoyl chloride Yamaguchi reagent Go
3-(ethyliminomethylideneamino)-N,N-dimethylpropane-1-amine, hydrochloride Go
3-[Bis(dimethylamino)methyliumyl]-3H-benzotriazol-1-oxide hexafluorophosphate HBTU Go
3-hydroxy-1,2,3-benzotriazin-4(3H)-one HOOBT Go
4-(4,6-Dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholin-4-ium chloride DMTMM Go
4-nitrophenyl chloroformate 4-NPC Go
4-nitrophenylchloroformate ClCO2C6H4NO2 Go
benzotriazol-1-yloxytripyrrolidinophosphonium hexafluorophosphate PyBOP Go
bis(2-oxo-3-oxazolidinyl)phosphinic chloride BOP-Cl Go
bromo(tripyrrolidin-1-yl)phosphonium hexafluorophosphate PyBroP Go
Bromotris(dimethylamino)phosphonium hexafluorophosphate BrOP Go
Carbonyldiimidazole CDI Go
diethyl phosphorocyanidate DEPC Go
Ethyl cyanohydroxyiminoacetate oxyma Go
ethyl cyanohydroxyiminoacetate oxyma Go
Fluoro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate TFFH Go
Hexachlorophosphazene (NPCl2)3 Go
Hydroxybenzotriazole HOBt Go
Hydroxybenzotriazole hydrate HOBt.H2O Go